Begin by softening your butter and spreading it generously on one side of each slice of bread. Sprinkle the buttered sides evenly with garlic powder and Italian seasoning, ensuring each bite of your Pizza Grilled Cheese bursts with flavor. Set the prepared bread aside while you gather the rest of your ingredients.

On a clean flat surface, lay two slices of bread buttered side down. Spread a thin layer of marinara sauce on each piece, ensuring to cover the surface evenly without soaking the bread. Next, layer one slice with a generous amount of shredded mozzarella, grated Parmesan, and turkey pepperoni, before adding any customized toppings you desire. Finish with the remaining slices of bread, buttered side up.

Heat a non-stick skillet over medium-low heat, allowing it to warm up for a minute or two. Carefully place your assembled Pizza Grilled Cheese in the skillet and cook for about 3-4 minutes, gently pressing down with a spatula to help everything meld together.

Using your spatula, carefully flip each sandwich and monitor the cooking progress. Cook for an additional 3-4 minutes, keeping an eye on the bread to ensure it turns a luscious golden brown while the cheese inside begins to ooze and melt.

Once both sides are perfectly toasted, remove the sandwiches from the skillet and let them cool for a minute. Slice each sandwich in half to reveal the melty interior, and if you'd like, garnish with fresh basil for a pop of color and flavor. Serve with warmed marinara sauce on the side for dipping.